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Responses to Environmental Enrichment Differ with Sex and Genotype in a Transgenic Mouse Model of Huntington's Disease

BACKGROUND: Environmental enrichment (EE) in laboratory animals improves neurological function and motor/cognitive performance, and is proposed as a strategy for treating neurodegenerative diseases. EE has been investigated in the R6/2 mouse model of Huntington's disease (HD), where increased s...

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Detalles Bibliográficos
Autores principales: Wood, Nigel I., Carta, Valentina, Milde, Stefan, Skillings, Elizabeth A., McAllister, Catherine J., Ang, Y.L. Mabel, Duguid, Alasdair, Wijesuriya, Nadeev, Afzal, Samira Mohd, Fernandes, Joe X., Leong, T.W., Morton, Jennifer
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820540/
https://www.ncbi.nlm.nih.gov/pubmed/20174443
http://dx.doi.org/10.1371/journal.pone.0009077