Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

Human genetic variation is the incarnation of diverse evolutionary history, which reflects both selectively advantageous and selectively neutral change. In this study, we catalogue structural and functional features of proteins that restrain genetic variation leading to single amino acid substitutio...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Sungsam, Blundell, Tom L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820541/
https://www.ncbi.nlm.nih.gov/pubmed/20169194
http://dx.doi.org/10.1371/journal.pone.0009186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820541/
https://www.ncbi.nlm.nih.gov/pubmed/20169194
http://dx.doi.org/10.1371/journal.pone.0009186

Ejemplares similares