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Rho Kinases Regulate the Renewal and Neural Differentiation of Embryonic Stem Cells in a Cell Plating Density–Dependent Manner

BACKGROUND: Rho kinases (ROCKs) mediate cell contraction, local adhesion, and cell motility, which are considered to be important in cell differentiation. We postulated that ROCKs are involved in controlling embryonic stem (ES) cell renewal and differentiation. METHODOLOGY/PRINCIPAL FINDINGS: CCE, a...

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Detalles Bibliográficos
Autores principales: Chang, Tzu-Ching, Chen, Yen-Chung, Yang, Ming-Hua, Chen, Chien-Hung, Hsing, En-Wei, Ko, Bor-Sheng, Liou, Jun-Yang, Wu, Kenneth K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820554/
https://www.ncbi.nlm.nih.gov/pubmed/20169147
http://dx.doi.org/10.1371/journal.pone.0009187