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Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling

Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We employed integrative molecular profiling to discover and characterize molecular subtypes of LMS. Gene expression profiling was performed on 51 LMS samples. Unsupervised clustering dem...

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Detalles Bibliográficos
Autores principales: Beck, Andrew H, Lee, Cheng-Han, Witten, Daniela M, Gleason, Briana C, Edris, Badreddin, Espinosa, Inigo, Zhu, Shirley, Li, Rui, Montgomery, Kelli D, Marinelli, Robert J, Tibshirani, Robert, Hastie, Trevor, Jablons, David M, Rubin, Brian P, Fletcher, Christopher D, West, Robert B, van de Rijn, Matt
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820592/
https://www.ncbi.nlm.nih.gov/pubmed/19901961
http://dx.doi.org/10.1038/onc.2009.381