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RNA-Seq gene expression estimation with read mapping uncertainty

Motivation: RNA-Seq is a promising new technology for accurately measuring gene expression levels. Expression estimation with RNA-Seq requires the mapping of relatively short sequencing reads to a reference genome or transcript set. Because reads are generally shorter than transcripts from which the...

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Detalles Bibliográficos
Autores principales: Li, Bo, Ruotti, Victor, Stewart, Ron M., Thomson, James A., Dewey, Colin N.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820677/
https://www.ncbi.nlm.nih.gov/pubmed/20022975
http://dx.doi.org/10.1093/bioinformatics/btp692