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Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development

BACKGROUND: The J-domain-containing protein auxilin, a critical regulator in clathrin-mediated transport, has been implicated in Drosophila Notch signaling. To ask if this role of auxilin is conserved and whether auxilin has additional roles in development, we have investigated the functions of auxi...

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Detalles Bibliográficos
Autores principales: Bai, Ting, Seebald, Jamie L, Kim, Kyu-Eui, Ding, Hong-Mei, Szeto, Daniel P, Chang, Henry C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821301/
https://www.ncbi.nlm.nih.gov/pubmed/20082716
http://dx.doi.org/10.1186/1471-213X-10-7