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The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer

BACKGROUND: The production of ascites is a common complication of ovarian cancer. Ascites constitute a unique tumor microenvironment that may affect disease progression. In this context, we recently showed that ovarian cancer ascites may protect tumor cells from TRAIL-induced apoptosis. In this stud...

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Detalles Bibliográficos
Autores principales: Lane, Denis, Matte, Isabelle, Rancourt, Claudine, Piché, Alain
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821314/
https://www.ncbi.nlm.nih.gov/pubmed/20157422
http://dx.doi.org/10.1186/1757-2215-3-1