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The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer
BACKGROUND: The production of ascites is a common complication of ovarian cancer. Ascites constitute a unique tumor microenvironment that may affect disease progression. In this context, we recently showed that ovarian cancer ascites may protect tumor cells from TRAIL-induced apoptosis. In this stud...
Autores principales: | Lane, Denis, Matte, Isabelle, Rancourt, Claudine, Piché, Alain |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821314/ https://www.ncbi.nlm.nih.gov/pubmed/20157422 http://dx.doi.org/10.1186/1757-2215-3-1 |
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