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Assembly complexity of prokaryotic genomes using short reads

BACKGROUND: De Bruijn graphs are a theoretical framework underlying several modern genome assembly programs, especially those that deal with very short reads. We describe an application of de Bruijn graphs to analyze the global repeat structure of prokaryotic genomes. RESULTS: We provide the first s...

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Detalles Bibliográficos
Autores principales: Kingsford, Carl, Schatz, Michael C, Pop, Mihai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821320/
https://www.ncbi.nlm.nih.gov/pubmed/20064276
http://dx.doi.org/10.1186/1471-2105-11-21