Structural Ordering of Disordered Ligand-Binding Loops of Biotin Protein Ligase into Active Conformations as a Consequence of Dehydration

Mycobacterium tuberculosis (Mtb), a dreaded pathogen, has a unique cell envelope composed of high fatty acid content that plays a crucial role in its pathogenesis. Acetyl Coenzyme A Carboxylase (ACC), an important enzyme that catalyzes the first reaction of fatty acid biosynthesis, is biotinylated b...

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Detalles Bibliográficos
Autores principales: Gupta, Vibha, Gupta, Rakesh K., Khare, Garima, Salunke, Dinakar M., Surolia, Avadhesha, Tyagi, Anil K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821413/
https://www.ncbi.nlm.nih.gov/pubmed/20169168
http://dx.doi.org/10.1371/journal.pone.0009222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821413/
https://www.ncbi.nlm.nih.gov/pubmed/20169168
http://dx.doi.org/10.1371/journal.pone.0009222

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