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Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes

Connective tissue growth factor (CTGF), also known as CCN2, is implicated in fibrosis through both extracellular matrix (ECM) induction and inhibition of ECM degradation. The role of CTGF in inflammation in cardiomyocytes is unknown. In some mesenchymal cell systems, CTGF mediates effects through TG...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyu, McLennan, Susan V., Allen, Terri J., Twigg, Stephen M.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821474/
https://www.ncbi.nlm.nih.gov/pubmed/20195389
http://dx.doi.org/10.1007/s12079-009-0083-1