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Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase
Oxidation and glycation of low-density lipoprotein (LDL) promote vascular injury in diabetes; however, the mechanisms underlying this effect remain poorly defined. The present study was conducted to determine the effects of ‘heavily oxidized’ glycated LDL (HOG-LDL) on endothelial nitric oxide syntha...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821526/ https://www.ncbi.nlm.nih.gov/pubmed/18624772 http://dx.doi.org/10.1111/j.1582-4934.2008.00416.x |