Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase

Oxidation and glycation of low-density lipoprotein (LDL) promote vascular injury in diabetes; however, the mechanisms underlying this effect remain poorly defined. The present study was conducted to determine the effects of ‘heavily oxidized’ glycated LDL (HOG-LDL) on endothelial nitric oxide syntha...

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Detalles Bibliográficos
Autores principales: Dong, Yunzhou, Wu, Yong, Wu, Mingyuan, Wang, Shuangxi, Zhang, Junhua, Xie, Zhonglin, Xu, Jian, Song, Ping, Wilson, Kenneth, Zhao, Zhengxing, Lyons, Timothy, Zou, Ming-Hui
Formato: Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821526/
https://www.ncbi.nlm.nih.gov/pubmed/18624772
http://dx.doi.org/10.1111/j.1582-4934.2008.00416.x

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