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Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response

The endoplasmic reticulum (ER) is the site of folding of membrane and secreted proteins in the cell. Physiological or pathological processes that disturb protein folding in the endoplasmic reticulum cause ER stress and activate a set of signaling pathways termed the Unfolded Protein Response (UPR)....

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Detalles Bibliográficos
Autores principales: Samali, Afshin, FitzGerald, Una, Deegan, Shane, Gupta, Sanjeev
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821749/
https://www.ncbi.nlm.nih.gov/pubmed/20169136
http://dx.doi.org/10.1155/2010/830307