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Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management

In the Western world, endometrial cancer (EC) is the most common malignant tumor of the female genital tract. Solid tumors like EC outgrow their vasculature resulting in hypoxia. Tumor hypoxia is important because it renders an aggressive phenotype and leads to radio- and chemo-therapy resistance. H...

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Detalles Bibliográficos
Autores principales: Seeber, Laura M. S., Zweemer, Ronald P., Verheijen, René H. M., van Diest, Paul J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821774/
https://www.ncbi.nlm.nih.gov/pubmed/20169098
http://dx.doi.org/10.1155/2010/580971