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Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management
In the Western world, endometrial cancer (EC) is the most common malignant tumor of the female genital tract. Solid tumors like EC outgrow their vasculature resulting in hypoxia. Tumor hypoxia is important because it renders an aggressive phenotype and leads to radio- and chemo-therapy resistance. H...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821774/ https://www.ncbi.nlm.nih.gov/pubmed/20169098 http://dx.doi.org/10.1155/2010/580971 |