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Airway smooth muscle proliferation and survival is not modulated by mast cells

BACKGROUND: Airway smooth muscle (ASM) hyperplasia and mast cell localization within the ASM bundle are important features of asthma. The cause of this increased ASM mass is uncertain and whether it is a consequence of ASM–mast cell interactions is unknown. OBJECTIVE: We sought to investigate ASM pr...

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Detalles Bibliográficos
Autores principales: Kaur, D, Hollins, F, Saunders, R, Woodman, L, Sutcliffe, A, Cruse, G, Bradding, P, Brightling, C
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821816/
https://www.ncbi.nlm.nih.gov/pubmed/20030664
http://dx.doi.org/10.1111/j.1365-2222.2009.03423.x