Carboxy Terminal Tail of Polycystin-1 Regulates Localization of TSC2 to Repress mTOR

Autosomal dominant polycystic kidney disease (ADPKD) is a commonly inherited renal disorder caused by defects in the PKD1 or PKD2 genes. ADPKD is associated with significant morbidity, and is a major underlying cause of end-stage renal failure (ESRF). Commonly, treatment options are limited to the m...

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Detalles Bibliográficos
Autores principales: Dere, Ruhee, Wilson, Patricia D., Sandford, Richard N., Walker, Cheryl Lyn
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821926/
https://www.ncbi.nlm.nih.gov/pubmed/20169078
http://dx.doi.org/10.1371/journal.pone.0009239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821926/
https://www.ncbi.nlm.nih.gov/pubmed/20169078
http://dx.doi.org/10.1371/journal.pone.0009239

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