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Selective Serotonin Reuptake Inhibitors Potentiate the Rapid Antidepressant-Like Effects of Serotonin(4) Receptor Agonists in the Rat

BACKGROUND: We have recently reported that serotonin(4) (5-HT(4)) receptor agonists have a promising potential as fast-acting antidepressants. Here, we assess the extent to which this property may be optimized by the concomitant use of conventional antidepressants. METHODOLOGY/PRINCIPAL FINDINGS: We...

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Detalles Bibliográficos
Autores principales: Lucas, Guillaume, Du, Jenny, Romeas, Thomas, Mnie-Filali, Ouissame, Haddjeri, Nasser, Piñeyro, Graciela, Debonnel, Guy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821932/
https://www.ncbi.nlm.nih.gov/pubmed/20169084
http://dx.doi.org/10.1371/journal.pone.0009253