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Disruption of PPARγ signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy

Peroxisome proliferator-activated receptor-gamma (PPARγ) regulates the interface between cellular lipid metabolism, redox status and organelle differentiation. Conditional prostatic epithelial knockout of PPARγ in mice resulted in focal hyperplasia which developed into mouse prostatic intraepithelia...

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Detalles Bibliográficos
Autores principales: Jiang, Ming, Fernandez, Suzanne, Jerome, W. Gray, He, Yue, Yu, Xiuping, Cai, Hui, Boone, Braden, Yi, Yajun, Magnuson, Mark A., Roy-Burman, Pradip, Matusik, Robert J., Shappell, Scott B., Hayward, Simon W.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821953/
https://www.ncbi.nlm.nih.gov/pubmed/19834493
http://dx.doi.org/10.1038/cdd.2009.148