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Disruption of PPARγ signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy
Peroxisome proliferator-activated receptor-gamma (PPARγ) regulates the interface between cellular lipid metabolism, redox status and organelle differentiation. Conditional prostatic epithelial knockout of PPARγ in mice resulted in focal hyperplasia which developed into mouse prostatic intraepithelia...
Autores principales: | Jiang, Ming, Fernandez, Suzanne, Jerome, W. Gray, He, Yue, Yu, Xiuping, Cai, Hui, Boone, Braden, Yi, Yajun, Magnuson, Mark A., Roy-Burman, Pradip, Matusik, Robert J., Shappell, Scott B., Hayward, Simon W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821953/ https://www.ncbi.nlm.nih.gov/pubmed/19834493 http://dx.doi.org/10.1038/cdd.2009.148 |
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