IGF-IR dependent expression of Survivin is required for T-Antigen mediated Protection from Apoptosis and Proliferation of Neural Progenitors

The Insulin-like Growth Factor-1 Receptor (IGF-IR) and the human polyomavirus JCV protein, T-Antigen cooperate in the transformation of neuronal precursors in the cerebellum, which may be a contributing factor in the development of brain tumors. Since it is not clear why T-Antigen requires IGF-IR fo...

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Detalles Bibliográficos
Autores principales: Gualco, Elisa, Urbanska, Katarzyna, Perez-Liz, Georgina, Sweet, Thersa, Peruzzi, Francesca, Reiss, Krzysztof, Valle, Luis Del
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822053/
https://www.ncbi.nlm.nih.gov/pubmed/19834489
http://dx.doi.org/10.1038/cdd.2009.146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822053/
https://www.ncbi.nlm.nih.gov/pubmed/19834489
http://dx.doi.org/10.1038/cdd.2009.146

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