VEGF-dependent tumor angiogenesis requires the inverse and reciprocal regulation of VEGFR1 and VEGFR2

Vascular endothelial growth factor (VEGF) signaling is critical for tumor angiogenesis. However, therapies based on the inhibition of VEGF receptors have shown modest results in patients with cancer. Surprisingly little is known about mechanisms underlying the regulation of VEGFR1 and VEGFR2 express...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaocheng, Neiva, Kathleen G., Lingen, Mark W., Ellis, Lee M., Nör, Jacques E.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822115/
https://www.ncbi.nlm.nih.gov/pubmed/19834490
http://dx.doi.org/10.1038/cdd.2009.152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822115/
https://www.ncbi.nlm.nih.gov/pubmed/19834490
http://dx.doi.org/10.1038/cdd.2009.152

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