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Iatrogenic QT Abnormalities and Fatal Arrhythmias: Mechanisms and Clinical Significance
Severe and occasionally fatal arrhythmias, commonly presenting as Torsade de Pointes [TdP] have been reported with Class III-antiarrhythmics, but also with non-antiarrhythmic drugs. Most cases result from an action on K(+) channels encoded by the HERG gene responsible for the IKr repolarizing curren...
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| Formato: | Texto |
| Lenguaje: | English |
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Bentham Science Publishers Ltd.
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822139/ https://www.ncbi.nlm.nih.gov/pubmed/20676275 http://dx.doi.org/10.2174/157340309788970397 |