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Iatrogenic QT Abnormalities and Fatal Arrhythmias: Mechanisms and Clinical Significance

Severe and occasionally fatal arrhythmias, commonly presenting as Torsade de Pointes [TdP] have been reported with Class III-antiarrhythmics, but also with non-antiarrhythmic drugs. Most cases result from an action on K(+) channels encoded by the HERG gene responsible for the IKr repolarizing curren...

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Detalles Bibliográficos
Autor principal: Cubeddu, Luigi X
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822139/
https://www.ncbi.nlm.nih.gov/pubmed/20676275
http://dx.doi.org/10.2174/157340309788970397

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