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Highly Expressed and Slowly Evolving Proteins Share Compositional Properties with Thermophilic Proteins

The sequences of proteins encoded by a genome evolve at different rates. A correlate of a protein's evolutionary rate is its expression level: highly expressed proteins tend to evolve slowly. Some explanations of rate variation and the correlation between rate and expression predict that more s...

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Detalles Bibliográficos
Autor principal: Cherry, Joshua L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822289/
https://www.ncbi.nlm.nih.gov/pubmed/19910385
http://dx.doi.org/10.1093/molbev/msp270