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Mechanisms of chromosomal rearrangement in the human genome
Many human cancers are associated with characteristic chromosomal rearrangements, especially hematopoietic cancers such as leukemias and lymphomas. The first and most critical step in the rearrangement process is the induction of two DNA double-strand breaks (DSB). In all cases, at least one of the...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822523/ https://www.ncbi.nlm.nih.gov/pubmed/20158866 http://dx.doi.org/10.1186/1471-2164-11-S1-S1 |