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Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction

BACKGROUND: Tandem mass spectrometry (MS/MS) has become a standard method for identification of proteins extracted from biological samples but the huge number and the noise contamination of MS/MS spectra obstruct swift and reliable computer-aided interpretation. Typically, a minor fraction of the sp...

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Detalles Bibliográficos
Autores principales: Mujezinovic, Nedim, Schneider, Georg, Wildpaner, Michael, Mechtler, Karl, Eisenhaber, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822527/
https://www.ncbi.nlm.nih.gov/pubmed/20158870
http://dx.doi.org/10.1186/1471-2164-11-S1-S13