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Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction
BACKGROUND: Tandem mass spectrometry (MS/MS) has become a standard method for identification of proteins extracted from biological samples but the huge number and the noise contamination of MS/MS spectra obstruct swift and reliable computer-aided interpretation. Typically, a minor fraction of the sp...
Autores principales: | Mujezinovic, Nedim, Schneider, Georg, Wildpaner, Michael, Mechtler, Karl, Eisenhaber, Frank |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822527/ https://www.ncbi.nlm.nih.gov/pubmed/20158870 http://dx.doi.org/10.1186/1471-2164-11-S1-S13 |
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