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Glycosidase inhibition: assessing mimicry of the transition state
Glycoside hydrolases, the enzymes responsible for hydrolysis of the glycosidic bond in di-, oligo- and polysaccharides, and glycoconjugates, are ubiquitous in Nature and fundamental to existence. The extreme stability of the glycosidic bond has meant these enzymes have evolved into highly proficient...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Royal Society of Chemistry
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822703/ https://www.ncbi.nlm.nih.gov/pubmed/20066263 http://dx.doi.org/10.1039/b915870g |