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Systematic analysis, comparison, and integration of disease based human genetic association data and mouse genetic phenotypic information

BACKGROUND: The genetic contributions to human common disorders and mouse genetic models of disease are complex and often overlapping. In common human diseases, unlike classical Mendelian disorders, genetic factors generally have small effect sizes, are multifactorial, and are highly pleiotropic. Li...

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Detalles Bibliográficos
Autores principales: Zhang, Yonqing, De, Supriyo, Garner, John R, Smith, Kirstin, Wang, S Alex, Becker, Kevin G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822734/
https://www.ncbi.nlm.nih.gov/pubmed/20092628
http://dx.doi.org/10.1186/1755-8794-3-1