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A genetic screen for modifiers of Drosophila caspase Dcp-1 reveals caspase involvement in autophagy and novel caspase-related genes

BACKGROUND: Caspases are cysteine proteases with essential functions in the apoptotic pathway; their proteolytic activity toward various substrates is associated with the morphological changes of cells. Recent reports have described non-apoptotic functions of caspases, including autophagy. In this r...

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Detalles Bibliográficos
Autores principales: Kim, Young-Il, Ryu, Taewoo, Lee, Judong, Heo, Young-Shin, Ahnn, Joohong, Lee, Seung-Jae, Yoo, OokJoon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822743/
https://www.ncbi.nlm.nih.gov/pubmed/20100334
http://dx.doi.org/10.1186/1471-2121-11-9