Role of reactive oxygen species in brucein D-mediated p38-mitogen-activated protein kinase and nuclear factor-κB signalling pathways in human pancreatic adenocarcinoma cells

BACKGROUND: In human pancreatic adenocarcinoma, nuclear factor-kappa-B (NF-κB) transcription factor is constitutively activated that contributes to the resistance of the tumour cells to induced apoptosis. In our earlier studies, we have shown that brucein D (BD) mediated apoptosis through activation...

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Detalles Bibliográficos
Autores principales: Lau, S T, Lin, Z X, Leung, P S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822930/
https://www.ncbi.nlm.nih.gov/pubmed/20068565
http://dx.doi.org/10.1038/sj.bjc.6605487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822930/
https://www.ncbi.nlm.nih.gov/pubmed/20068565
http://dx.doi.org/10.1038/sj.bjc.6605487

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