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Considerations for the use of plasma cytokeratin 18 as a biomarker in pancreatic cancer

BACKGROUND: Enzyme-linked immunoassays of full-length (M65) and/or caspase-cleaved (M30) cytokeratin 18 (CK18) released from epithelial cells undergoing necrosis and/or apoptosis, respectively, may have prognostic or predictive biomarker utility in a range of solid tumour types. Characterisation of...

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Detalles Bibliográficos
Autores principales: Dive, C, Smith, R A, Garner, E, Ward, T, George-Smith, S St, Campbell, F, Greenhalf, W, Ghaneh, P, Neoptolemos, J P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822934/
https://www.ncbi.nlm.nih.gov/pubmed/20051949
http://dx.doi.org/10.1038/sj.bjc.6605494