A novel fragment derived from the β chain of human fibrinogen, β43–63, is a potent inhibitor of activated endothelial cells in vitro and in vivo

BACKGROUND: Angiogenesis and haemostasis are closely linked within tumours with many haemostatic proteins regulating tumour angiogenesis. Indeed we previously identified a fragment of human fibrinogen, fibrinogen E-fragment (FgnE) with potent anti-angiogenic properties in vitro and cytotoxic effects...

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Detalles Bibliográficos
Autores principales: Krajewska, E, Lewis, C E, Chen, Y-Y, Welford, A, Tazzyman, S, Staton, C A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822935/
https://www.ncbi.nlm.nih.gov/pubmed/20068569
http://dx.doi.org/10.1038/sj.bjc.6605495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822935/
https://www.ncbi.nlm.nih.gov/pubmed/20068569
http://dx.doi.org/10.1038/sj.bjc.6605495

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