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The role of folate receptor alpha (FRα) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy

BACKGROUND: The standard treatment of choice for malignant pleural mesothelioma is chemotherapy with pemetrexed and platinum, but the clinical outcome is poor. This study investigates the response to pemetrexed in a panel of eight mesothelioma cell lines and the clinical outcome for patients treated...

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Detalles Bibliográficos
Autores principales: Nutt, J E, Razak, A R A, O'Toole, K, Black, F, Quinn, A E, Calvert, A H, Plummer, E R, Lunec, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822938/
https://www.ncbi.nlm.nih.gov/pubmed/20051956
http://dx.doi.org/10.1038/sj.bjc.6605501