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Rolipram, a Phosphodiesterase 4 Inhibitor, Stimulates Inducible cAMP Early Repressor Expression in Osteoblasts

Phosphodiesterase (PDE) 4 inhibitors have been shown to induce the cAMP-mediated signaling pathway by inhibiting cAMP hydrolysis. This study investigated the effect of a PDE4 inhibitor on the expression of the inducible cAMP early repressor (ICER), which is an endogenous inhibitor of CRE-mediated tr...

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Detalles Bibliográficos
Autores principales: Cho, Eun Sook, Yu, Ja Heon, Kim, Mi Sun, Yim, Mijung
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823041/
https://www.ncbi.nlm.nih.gov/pubmed/15744818
http://dx.doi.org/10.3349/ymj.2005.46.1.149