Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

Craniorachischisis is a rare but severe birth defect that results in a completely open neural tube. Mouse mutants in planar cell polarity (PCP) signaling components have deficits in the morphological movements of convergent extension (CE) that result in craniorachischisis. Using a forward-genetic sc...

Descripción completa

Detalles Bibliográficos
Autores principales: Merte, Janna, Jensen, Devon, Wright, Kevin, Sarsfield, Sarah, Wang, Yanshu, Schekman, Randy, Ginty, David D.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823131/
https://www.ncbi.nlm.nih.gov/pubmed/19966784
http://dx.doi.org/10.1038/ncb2002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823131/
https://www.ncbi.nlm.nih.gov/pubmed/19966784
http://dx.doi.org/10.1038/ncb2002

Ejemplares similares