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Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

Craniorachischisis is a rare but severe birth defect that results in a completely open neural tube. Mouse mutants in planar cell polarity (PCP) signaling components have deficits in the morphological movements of convergent extension (CE) that result in craniorachischisis. Using a forward-genetic sc...

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Detalles Bibliográficos
Autores principales:	Merte, Janna, Jensen, Devon, Wright, Kevin, Sarsfield, Sarah, Wang, Yanshu, Schekman, Randy, Ginty, David D.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823131/ https://www.ncbi.nlm.nih.gov/pubmed/19966784 http://dx.doi.org/10.1038/ncb2002

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