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Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish

Although DNA methylation is critical for proper embryonic and tissue-specific development, how different DNA methyltransferases affect tissue-specific development and their targets remains unknown. We address this issue in zebrafish through antisense-based morpholino knockdown of Dnmt3 and Dnmt1. Ou...

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Detalles Bibliográficos
Autores principales: Rai, Kunal, Jafri, Itrat F., Chidester, Stephanie, James, Smitha R., Karpf, Adam R., Cairns, Bradley R., Jones, David A.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823551/
https://www.ncbi.nlm.nih.gov/pubmed/19946145
http://dx.doi.org/10.1074/jbc.M109.073676