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IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients

BACKGROUND: Insulin-like growth factor-1 (IGF-I) signalling is important for cancer initiation and progression. Given the emerging evidence for the role of the stroma in these processes, we aimed to characterize the effects of IGF-I on cancer cells and stromal cells separately. METHODS: We used an e...

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Detalles Bibliográficos
Autores principales: Rajski, Michal, Zanetti-Dällenbach, Rosanna, Vogel, Brigitte, Herrmann, Richard, Rochlitz, Christoph, Buess, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823652/
https://www.ncbi.nlm.nih.gov/pubmed/20051100
http://dx.doi.org/10.1186/1741-7015-8-1