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An M2e-based multiple antigenic peptide vaccine protects mice from lethal challenge with divergent H5N1 influenza viruses

BACKGROUND: A growing concern has raised regarding the pandemic potential of the highly pathogenic avian influenza (HPAI) H5N1 viruses. Consequently, there is an urgent need to develop an effective and safe vaccine against the divergent H5N1 influenza viruses. In the present study, we designed a tet...

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Detalles Bibliográficos
Autores principales: Zhao, Guangyu, Lin, Yongping, Du, Lanying, Guan, Jie, Sun, Shihui, Sui, Hongyan, Kou, Zhihua, Chan, Chris CS, Guo, Yan, Jiang, Shibo, Zheng, Bo-Jian, Zhou, Yusen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823673/
https://www.ncbi.nlm.nih.gov/pubmed/20082709
http://dx.doi.org/10.1186/1743-422X-7-9