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Modulatory effects of cAMP and PKC activation on gap junctional intercellular communication among thymic epithelial cells

BACKGROUND: We investigated the effects of the signaling molecules, cyclic AMP (cAMP) and protein-kinase C (PKC), on gap junctional intercellular communication (GJIC) between thymic epithelial cells (TEC). RESULTS: Treatment with 8-Br-cAMP, a cAMP analog; or forskolin, which stimulates cAMP producti...

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Detalles Bibliográficos
Autores principales: Nihei, Oscar K, Fonseca, Paula C, Rubim, Nara M, Bonavita, Andre G, Lyra, Jurandy SPO, Neves-dos-Santos, Sandra, de Carvalho, Antonio C Campos, Spray, David C, Savino, Wilson, Alves, Luiz A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823718/
https://www.ncbi.nlm.nih.gov/pubmed/20078861
http://dx.doi.org/10.1186/1471-2121-11-3