The Virion Host Shut-Off (vhs) Protein Blocks a TLR-Independent Pathway of Herpes Simplex Virus Type 1 Recognition in Human and Mouse Dendritic Cells

Molecular pathways underlying the activation of dendritic cells (DCs) in response to Herpes Simplex Virus type 1 (HSV-1) are poorly understood. Removal of the HSV virion host shut-off (vhs) protein relieves a block to DC activation observed during wild-type infection. In this study, we utilized a po...

Descripción completa

Detalles Bibliográficos
Autores principales: Cotter, Christopher R., Nguyen, Marie L., Yount, Jacob S., López, Carolina B., Blaho, John A., Moran, Thomas M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823768/
https://www.ncbi.nlm.nih.gov/pubmed/20174621
http://dx.doi.org/10.1371/journal.pone.0008684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823768/
https://www.ncbi.nlm.nih.gov/pubmed/20174621
http://dx.doi.org/10.1371/journal.pone.0008684

Ejemplares similares