Cargando…
The Virion Host Shut-Off (vhs) Protein Blocks a TLR-Independent Pathway of Herpes Simplex Virus Type 1 Recognition in Human and Mouse Dendritic Cells
Molecular pathways underlying the activation of dendritic cells (DCs) in response to Herpes Simplex Virus type 1 (HSV-1) are poorly understood. Removal of the HSV virion host shut-off (vhs) protein relieves a block to DC activation observed during wild-type infection. In this study, we utilized a po...
Autores principales: | Cotter, Christopher R., Nguyen, Marie L., Yount, Jacob S., López, Carolina B., Blaho, John A., Moran, Thomas M. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823768/ https://www.ncbi.nlm.nih.gov/pubmed/20174621 http://dx.doi.org/10.1371/journal.pone.0008684 |
Ejemplares similares
-
Multiple Posttranscriptional Strategies To Regulate the Herpes Simplex Virus 1 vhs Endoribonuclease
por: Elliott, Gillian, et al.
Publicado: (2018) -
Herpes Simplex Virus 1 Expressing GFP-Tagged Virion Host Shutoff (vhs) Protein Uncouples the Activities of RNA Degradation and Differential Nuclear Retention of the Virus Transcriptome
por: Wise, Emma L., et al.
Publicado: (2022) -
Herpes simplex virus blocks apoptosis by precluding mitochondrial cytochrome c release independent of caspase activation in infected human epithelial cells
por: Aubert, Martine, et al.
Publicado: (2006) -
Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off
por: Dremel, Sarah E, et al.
Publicado: (2019) -
VHS, US3 and UL13 viral tegument proteins are required for Herpes Simplex Virus-Induced modification of protein kinase R
por: Pennisi, Rosamaria, et al.
Publicado: (2020)