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Neutrophils Are Resistant to Yersinia YopJ/P-Induced Apoptosis and Are Protected from ROS-Mediated Cell Death by the Type III Secretion System

BACKGROUND: The human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disease in humans. In particular, the Yersinia outer...

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Detalles Bibliográficos
Autores principales: Spinner, Justin L., Seo, Keun Seok, O'Loughlin, Jason L., Cundiff, Jennifer A., Minnich, Scott A., Bohach, Gregory A., Kobayashi, Scott D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823771/
https://www.ncbi.nlm.nih.gov/pubmed/20174624
http://dx.doi.org/10.1371/journal.pone.0009279