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Conformational Dynamics and Ligand Binding in the Multi-Domain Protein PDC109
PDC109 is a modular multi-domain protein with two fibronectin type II (Fn2) repeats joined by a linker. It plays a major role in bull sperm binding to the oviductal epithelium through its interactions with phosphorylcholines (PhCs), a head group of sperm cell membrane lipids. The crystal structure o...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823774/ https://www.ncbi.nlm.nih.gov/pubmed/20174627 http://dx.doi.org/10.1371/journal.pone.0009180 |