Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin

BACKGROUND: The Notch pathway is essential for proper epidermal differentiation during embryonic skin development. Moreover, skin specific loss of Notch signaling in the embryo results in skin barrier defects accompanied by a B-lymphoproliferative disease. However, much less is known about the conse...

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Detalles Bibliográficos
Autores principales: Dumortier, Alexis, Durham, André-Dante, Di Piazza, Matteo, Vauclair, Sophie, Koch, Ute, Ferrand, Gisèle, Ferrero, Isabel, Demehri, Shadmehr, Song, Lynda Li, Farr, Andrew G., Leonard, Warren J., Kopan, Raphael, Miele, Lucio, Hohl, Daniel, Finke, Daniela, Radtke, Freddy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823782/
https://www.ncbi.nlm.nih.gov/pubmed/20174635
http://dx.doi.org/10.1371/journal.pone.0009258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823782/
https://www.ncbi.nlm.nih.gov/pubmed/20174635
http://dx.doi.org/10.1371/journal.pone.0009258

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