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A Role for S1P and S1P1 in Immature-B Cell Egress from Mouse Bone Marrow

B lymphocyte egress from secondary lymphoid organs requires sphingosine-1-phosphate (S1P) and S1P receptor-1 (S1P1). However, whether S1P contributes to immature-B cell egress from the bone marrow (BM) has not been fully assessed. Here we report that in S1P- and S1P1-conditionally deficient mice, th...

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Detalles Bibliográficos
Autores principales: Pereira, João Pedro, Cyster, Jason G., Xu, Ying
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823786/
https://www.ncbi.nlm.nih.gov/pubmed/20174580
http://dx.doi.org/10.1371/journal.pone.0009277