Cargando…

A comparative analysis of the fluorescence properties of the wild-type and active site mutants of the hepatitis C virus autoprotease NS2-3

Hepatitis C virus encodes an autoprotease, NS2-3, which is required for processing of the viral polyprotein between the non-structural NS2 and NS3 proteins. This protease activity is vital for the replication and assembly of the virus and therefore represents a target for the development of anti-vir...

Descripción completa

Detalles Bibliográficos
Autores principales: Foster, Toshana L., Tedbury, Philip R., Pearson, Arwen R., Harris, Mark
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824112/
https://www.ncbi.nlm.nih.gov/pubmed/19853065
http://dx.doi.org/10.1016/j.bbapap.2009.10.006