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A comparative analysis of the fluorescence properties of the wild-type and active site mutants of the hepatitis C virus autoprotease NS2-3
Hepatitis C virus encodes an autoprotease, NS2-3, which is required for processing of the viral polyprotein between the non-structural NS2 and NS3 proteins. This protease activity is vital for the replication and assembly of the virus and therefore represents a target for the development of anti-vir...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824112/ https://www.ncbi.nlm.nih.gov/pubmed/19853065 http://dx.doi.org/10.1016/j.bbapap.2009.10.006 |